Coronary Microcirculation
نویسندگان
چکیده
منابع مشابه
Coronary microcirculation: the new frontier in coronary artery disease
A large body of evidence challenges the common view which attributes myocardial ischemia entirely and exclusively to atherosclerotic obstructions of large epicardial coronary vessels. In animal model as well in man, altered vasomotor control at the microvascular level may aggravate the effects of epicardial obstructions and/or hinder myocardial perfusion even in the absence of a proximal obstru...
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Noncyclooxygenase metabolites of arachidonic acid (AA) have been proposed to mediate endothelium-dependent vasodilation in the coronary microcirculation. Therefore, we examined the formation and bioactivity of AA metabolites in porcine coronary (PC) microvascular endothelial cells and microvessels, respectively. The major noncyclooxygenase metabolite produced by microvascular endothelial cells ...
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The coronary circulation, responsible for the delivery of oxygen and other nutrients to the myocardium, is a complex system of conductance and resistance vessels. Each has its own mechanisms of dynamic regulation of its calibre through changes in the contractile state of the underlying smooth muscle. In addition, each plays a different role in determining myocardial perfusion in health and dise...
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THE QUESTION we are posing to the readers is why should we study the microcirculation of the heart. First, let us define who are “we.” In this issue of the American Journal of Physiology: Heart and Circulatory Physiology, a collection of papers are included as part of a Special Call on “Emerging Concepts in the Control of the Coronary Microcirculation.” It is obvious why the coronary microcircu...
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Microvascular damage is frequently observed in the setting of acute coronary syndromes (ACS). Imaging of the microcirculation is playing an increasingly important role in the risk stratification of patients presenting with acute coronary syndromes, furthering our understanding about coronary microcirculatory patho-physiology in this setting. Of the available imaging methods, cardiac magnetic re...
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ژورنال
عنوان ژورنال: Circulation Journal
سال: 2014
ISSN: 1346-9843,1347-4820
DOI: 10.1253/circj.cj-14-0539